PREPARATION OF PITUITARY THYROTROPIC HORMONE
نویسندگان
چکیده
منابع مشابه
Preparation of pituitary thyrotropic hormone.
The existence of a thyroid-stimulating hormone in anterior pituitary gland tissue has been known for 30 years (1, 2). During this time, considerable work has been done on the physiological and the pharmacological effects of the thyrotropic hormone administ’ered in the form of pituitary extracts which had been subjected t,o a varying degree of manipulation. Relatively little progress on the puri...
متن کاملPreparation of Pituitary Thyrotropic Hormone*
The existence of a thyroid-stimulating hormone in anterior pituitary gland tissue has been known for 30 years (1, 2). During this time, considerable work has been done on the physiological and the pharmacological effects of the thyrotropic hormone administ’ered in the form of pituitary extracts which had been subjected t,o a varying degree of manipulation. Relatively little progress on the puri...
متن کاملThe Intracellular Localization of Pituitary Thyrotropic Hormone
The intracellular localization of a bovine anterior pituitary preparation of thyroid-stimulating hormone (TSH) was studied in guinea pigs and dogs. The preparation was administered intravascularly or applied directly to tissue sections. TSH was detected by an indirect technique utilizing bovine TSH antiserum and fluorescein-labeled anti-rabbit globulin; the presence of TSH in the tissue was ind...
متن کاملStudies with mouse pituitary thyrotropic tumors. I. Survival of implants during prolonged suppression by thyroid hormone.
Implants of dependent mouse pituitary thyrotropic tumors survived prolonged suppression of growth with thyroid hormone. With one dependent strain, 805~, no tumor became palpable after implantation in control mice with intact thyroid to 17 months. However, tumors regularly appeared in implanted radiothyroidectomized mice. The latent period to appearance of the tumor decreased with increasing tim...
متن کاملExperiences with malignant exophthalmos. Relationship of the condition to thyrotoxicosis and to the pituitary thyrotropic hormone.
ANYONE confronted with a case of severe malignant exophthalmos, who searches the literature for guidance in therapy, must soon perceive the confusion of thought and experience that exists regarding this condition, the solution of which is one of the most pressing problems facing thyroid surgery today. By some, the administration of thyroid is claimed to cure the condition, while others recommen...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1945
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)51069-3